Cell cycle molecule Cdc25A and its role in Parkinson's disease related neurodegeneration
نویسندگان
چکیده
منابع مشابه
Cdc25A phosphatase: a key cell cycle protein that regulates neuron death in disease and development
Cell cycle molecules are mostly dormant in differentiated neurons that are post-mitotic and in the G0 state of the cell cycle. However, a wealth of evidence strongly suggests that in response to a wide variety of apoptotic stimuli, including trophic factor deprivation, exposure to β-amyloid (Aβ) and DNA damage, neurons emerge from theG0 state with aberrant expression/activation of cell cycle pr...
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ژورنال
عنوان ژورنال: IBRO Reports
سال: 2019
ISSN: 2451-8301
DOI: 10.1016/j.ibror.2019.07.1155